• All motifs sorted by activity significance
• All samples sorted alphabetically
• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
• Download the whole report

Motif ID: NFY{A,B,C}.p2

Z-value: 3.218

---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr16_-_2264776	7.277	NM_001042371	PGP	phosphoglycolate phosphatase
chr17_-_79818406	6.794		P4HB	prolyl 4-hydroxylase, beta polypeptide
chr17_-_79818444	6.689		P4HB	prolyl 4-hydroxylase, beta polypeptide
chr2_-_240322620	6.497	NM_006037	HDAC4	histone deacetylase 4
chr19_-_2042022	6.251		MKNK2	MAP kinase interacting serine/threonine kinase 2
chr17_-_79818370	6.054		P4HB	prolyl 4-hydroxylase, beta polypeptide
chr19_-_14228362	5.978	NM_002730	PRKACA	protein kinase, cAMP-dependent, catalytic, alpha
chr17_-_79818318	5.903		P4HB	prolyl 4-hydroxylase, beta polypeptide
chr17_-_79818418	5.845		P4HB	prolyl 4-hydroxylase, beta polypeptide
chr19_+_19174792	5.788	NM_178526	SLC25A42	solute carrier family 25, member 42
chr9_+_131843378	5.472	NM_001135917 NM_020438	DOLPP1	dolichyl pyrophosphate phosphatase 1
chr2_+_70142152	5.387	NM_001202513 NM_001202514 NM_002357	MXD1	MAX dimerization protein 1
chr1_+_25757381	5.324	NM_018202	TMEM57	transmembrane protein 57
chr19_-_14228560	5.195		PRKACA	protein kinase, cAMP-dependent, catalytic, alpha
chr14_+_24584467	5.139	NM_181357	DCAF11	DDB1 and CUL4 associated factor 11
chr1_+_227127937	4.793	NM_020247	ADCK3	aarF domain containing kinase 3
chr1_+_227127959	4.791		ADCK3	aarF domain containing kinase 3
chr19_+_50270068	4.723	NM_014203 NM_130787	AP2A1	adaptor-related protein complex 2, alpha 1 subunit
chr16_-_1832576	4.720	NM_080861	SPSB3	splA/ryanodine receptor domain and SOCS box containing 3
chr16_-_1832571	4.679		SPSB3	splA/ryanodine receptor domain and SOCS box containing 3
chr1_+_227127999	4.594		ADCK3	aarF domain containing kinase 3
chr19_-_2041862	4.549		MKNK2	MAP kinase interacting serine/threonine kinase 2
chr1_+_227127993	4.542		ADCK3	aarF domain containing kinase 3
chr16_-_1876528	4.425		HAGH	hydroxyacylglutathione hydrolase
chr17_+_1619816	4.412	NM_001163673 NM_152348	WDR81	WD repeat domain 81
chr17_+_46018888	4.396	NM_018129	PNPO	pyridoxamine 5'-phosphate oxidase
chr1_+_110881944	4.312	NM_001201545 NM_022768	RBM15	RNA binding motif protein 15
chr7_-_100183722	4.248		LRCH4	leucine-rich repeats and calponin homology (CH) domain containing 4
chr16_-_1832304	4.210		SPSB3	splA/ryanodine receptor domain and SOCS box containing 3
chr1_+_110882063	4.073		RBM15	RNA binding motif protein 15
chr2_-_96873938	3.911		STARD7	StAR-related lipid transfer (START) domain containing 7
chr2_-_240322692	3.891		HDAC4	histone deacetylase 4
chr2_+_70142303	3.782		MXD1	MAX dimerization protein 1
chr19_+_50270271	3.772		AP2A1	adaptor-related protein complex 2, alpha 1 subunit
chr3_+_67048726	3.764	NM_032505	KBTBD8	kelch repeat and BTB (POZ) domain containing 8
chrX_-_47004092	3.731	NM_001135998 NM_019056	NDUFB11	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa
chr14_-_73360792	3.727	NM_012074	DPF3	D4, zinc and double PHD fingers, family 3
chr1_+_44115828	3.716		KDM4A	lysine (K)-specific demethylase 4A
chr1_+_110882057	3.649		RBM15	RNA binding motif protein 15
chr6_-_42713837	3.586	NM_003192	TBCC	tubulin folding cofactor C
chr14_+_24584321	3.547		DCAF11	DDB1 and CUL4 associated factor 11
chr17_-_79818514	3.514	NM_000918	P4HB	prolyl 4-hydroxylase, beta polypeptide
chr6_+_20402040	3.503	NM_001949	E2F3	E2F transcription factor 3
chr7_+_6048902	3.503		AIMP2	aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
chr1_-_19229016	3.480	NM_003748 NM_170726	ALDH4A1	aldehyde dehydrogenase 4 family, member A1
chr3_-_186288096	3.460		TBCCD1	TBCC domain containing 1
chr19_+_4969123	3.449	NM_015015	KDM4B	lysine (K)-specific demethylase 4B
chr15_+_41523401	3.423	NM_007236	CHP	calcium binding protein P22
chr1_+_44115795	3.420	NM_014663	KDM4A	lysine (K)-specific demethylase 4A
chr9_-_35072643	3.393	NM_007126	VCP	valosin containing protein
chr9_-_35072596	3.384		VCP	valosin containing protein
chr3_-_186288331	3.368	NM_001134415	TBCCD1	TBCC domain containing 1
chr6_+_42897236	3.343		CNPY3	canopy 3 homolog (zebrafish)
chr1_-_52344010	3.336		NRD1	nardilysin (N-arginine dibasic convertase)
chr17_+_57233100	3.329		PRR11	proline rich 11
chr10_-_91403630	3.327	NM_138316 NM_148978	PANK1	pantothenate kinase 1
chr21_+_47744032	3.316	NM_006031	PCNT	pericentrin
chr6_+_42897184	3.290		CNPY3	canopy 3 homolog (zebrafish)
chr2_+_70142236	3.249		MXD1	MAX dimerization protein 1
chr2_-_71454200	3.248	NM_020459	PAIP2B	poly(A) binding protein interacting protein 2B
chr16_-_58663739	3.245	NM_016284 NM_206999	CNOT1	CCR4-NOT transcription complex, subunit 1
chr17_-_1532109	3.204	NM_152346	SLC43A2	solute carrier family 43, member 2
chr16_-_58663727	3.176		CNOT1	CCR4-NOT transcription complex, subunit 1
chr13_-_41240607	3.161	NM_002015	FOXO1	forkhead box O1
chr7_+_6048921	3.157		AIMP2	aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
chr2_-_73460326	3.148	NM_032319	PRADC1	protease-associated domain containing 1
chr1_+_181057835	3.135		IER5	immediate early response 5
chr11_+_13299372	3.132		ARNTL	aryl hydrocarbon receptor nuclear translocator-like
chr16_-_58663734	3.126		CNOT1	CCR4-NOT transcription complex, subunit 1
chr16_-_1877140	3.073	NM_001040427 NM_005326	HAGH	hydroxyacylglutathione hydrolase
chr1_+_44115804	3.041		KDM4A	lysine (K)-specific demethylase 4A
chr11_+_13299376	3.026		ARNTL	aryl hydrocarbon receptor nuclear translocator-like
chr14_+_24584009	3.022		DCAF11	DDB1 and CUL4 associated factor 11
chr11_+_34460421	3.020	NM_001752	CAT	catalase
chr11_+_13299329	3.012		ARNTL	aryl hydrocarbon receptor nuclear translocator-like
chr2_-_96874507	2.975		STARD7	StAR-related lipid transfer (START) domain containing 7
chr13_+_53029614	2.919		CKAP2	cytoskeleton associated protein 2
chr2_-_179672056	2.917	NM_003319 NM_133378 NM_133379 NM_133432 NM_133437	TTN	titin
chr7_+_129710336	2.882	NM_014997	KLHDC10	kelch domain containing 10
chr17_+_80416606	2.868		NARF	nuclear prelamin A recognition factor
chr16_-_11036215	2.863	NM_014015	DEXI	Dexi homolog (mouse)
chr1_+_6052758	2.859		KCNAB2	potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr11_+_13299260	2.850	NM_001030272 NM_001030273 NM_001178	ARNTL	aryl hydrocarbon receptor nuclear translocator-like
chr17_+_46019022	2.845		PNPO	pyridoxamine 5'-phosphate oxidase
chr7_+_6048858	2.839	NM_006303	AIMP2	aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
chr3_+_186288445	2.834	NM_016306	DNAJB11	DnaJ (Hsp40) homolog, subfamily B, member 11
chr19_+_50270263	2.825		AP2A1	adaptor-related protein complex 2, alpha 1 subunit
chr9_-_35815040	2.798	NM_032593	HINT2	histidine triad nucleotide binding protein 2
chr11_+_13299349	2.793		ARNTL	aryl hydrocarbon receptor nuclear translocator-like
chr5_-_95297597	2.782	NM_012081	ELL2	elongation factor, RNA polymerase II, 2
chr17_-_47841468	2.781		FAM117A	family with sequence similarity 117, member A
chr3_+_186288498	2.781		DNAJB11	DnaJ (Hsp40) homolog, subfamily B, member 11
chr17_-_74236272	2.780	NM_052916	RNF157	ring finger protein 157
chr15_-_76603806	2.764	NM_000126 NM_001127716	ETFA	electron-transfer-flavoprotein, alpha polypeptide
chr11_+_34460533	2.753		CAT	catalase
chr2_+_203499667	2.738		FAM117B	family with sequence similarity 117, member B
chr2_-_96874569	2.722	NM_020151	STARD7	StAR-related lipid transfer (START) domain containing 7
chr1_-_52344306	2.712		NRD1	nardilysin (N-arginine dibasic convertase)
chr19_-_10491212	2.707	NM_003331	TYK2	tyrosine kinase 2
chr14_+_24583979	2.695	NM_025230	DCAF11	DDB1 and CUL4 associated factor 11
chr17_+_4613931	2.693		ARRB2	arrestin, beta 2
chr9_-_35072545	2.691		VCP	valosin containing protein
chr14_+_24583905	2.689	NM_001163484	DCAF11	DDB1 and CUL4 associated factor 11
chr17_+_57232859	2.686	NM_018304	PRR11	proline rich 11
chr9_-_74525846	2.665		FAM108B1	family with sequence similarity 108, member B1
chr3_+_154797435	2.659	NM_000902	MME	membrane metallo-endopeptidase
chr3_-_119812973	2.656	NM_001146156 NM_002093	GSK3B	glycogen synthase kinase 3 beta
chr16_+_1832928	2.655	NM_012225	NUBP2	nucleotide binding protein 2
chr15_-_76603728	2.650		ETFA	electron-transfer-flavoprotein, alpha polypeptide
chr15_-_76603742	2.637		ETFA	electron-transfer-flavoprotein, alpha polypeptide
chr1_-_221915393	2.626		DUSP10	dual specificity phosphatase 10
chr16_-_1876792	2.621		HAGH	hydroxyacylglutathione hydrolase
chr5_+_70883100	2.611	NM_022132	MCCC2	methylcrotonoyl-CoA carboxylase 2 (beta)
chr3_-_49761293	2.611	NM_013334 NM_021971	GMPPB	GDP-mannose pyrophosphorylase B
chr19_+_4969126	2.604		KDM4B	lysine (K)-specific demethylase 4B
chr1_+_26560613	2.596	NM_022778	CEP85	centrosomal protein 85kDa
chr11_-_47198379	2.594		ARFGAP2	ADP-ribosylation factor GTPase activating protein 2
chrX_-_47004416	2.591		NDUFB11	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa
chr4_+_74269971	2.590	NM_000477	ALB	albumin
chr2_-_152590983	2.571	NM_001164507 NM_001164508 NM_004543	NEB	nebulin
chr1_-_151798552	2.557	NM_001001523	RORC	RAR-related orphan receptor C
chr6_-_166796363	2.554		BRP44L	brain protein 44-like
chr4_-_2263808	2.546		MXD4	MAX dimerization protein 4
chr17_+_45727274	2.542	NM_002265	KPNB1	karyopherin (importin) beta 1
chr15_-_76603791	2.531		ETFA	electron-transfer-flavoprotein, alpha polypeptide
chr2_-_61765394	2.531	NM_003400	XPO1	exportin 1 (CRM1 homolog, yeast)
chr16_+_50775960	2.527	NM_001042355 NM_015247	CYLD	cylindromatosis (turban tumor syndrome)
chr19_-_10491172	2.526		TYK2	tyrosine kinase 2
chrX_+_150151757	2.504	NM_005342	HMGB3	high mobility group box 3
chr1_+_43148048	2.499	NM_004559	YBX1	Y box binding protein 1
chr13_+_53029494	2.489	NM_001098525 NM_018204	CKAP2	cytoskeleton associated protein 2
chr11_-_73694297	2.488		UCP2	uncoupling protein 2 (mitochondrial, proton carrier)
chr17_+_46970128	2.485	NM_001002027 NM_005175	ATP5G1	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr9_-_123476578	2.478	NM_001080497	MEGF9	multiple EGF-like-domains 9
chrX_-_47004065	2.472		NDUFB11	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa
chr2_+_203499819	2.472	NM_173511	FAM117B	family with sequence similarity 117, member B
chr7_-_148725500	2.469		PDIA4	protein disulfide isomerase family A, member 4
chr3_-_160283071	2.465		KPNA4	karyopherin alpha 4 (importin alpha 3)
chr1_+_43148098	2.460		YBX1	Y box binding protein 1
chr16_-_11036155	2.436		DEXI	Dexi homolog (mouse)
chr17_+_45727303	2.418		KPNB1	karyopherin (importin) beta 1
chr1_-_109940497	2.407	NM_002959	SORT1	sortilin 1
chr1_+_145438437	2.407	NM_006472	TXNIP	thioredoxin interacting protein
chr3_+_154797644	2.399	NM_007287	MME	membrane metallo-endopeptidase
chr11_-_3013577	2.397	NM_005969	NAP1L4	nucleosome assembly protein 1-like 4
chr11_+_68228182	2.394	NM_001164160 NM_001164161 NM_001164162 NM_001164163 NM_001164164 NM_018312	PPP6R3	protein phosphatase 6, regulatory subunit 3
chrX_-_47509864	2.376		ELK1	ELK1, member of ETS oncogene family
chr1_-_221915458	2.370	NM_007207 NM_144729	DUSP10	dual specificity phosphatase 10
chr17_+_74261431	2.358		FAM100B	family with sequence similarity 100, member B
chr22_+_40440664	2.357	NM_001024843	TNRC6B	trinucleotide repeat containing 6B
chr1_+_150459873	2.351		TARS2	threonyl-tRNA synthetase 2, mitochondrial (putative)
chr16_+_1833003	2.324
chr9_+_34329503	2.314	NM_001161 NM_001244390 NM_147172 NM_147173	NUDT2	nudix (nucleoside diphosphate linked moiety X)-type motif 2
chr3_-_141868208	2.303	NM_001178138 NM_001178139	TFDP2	transcription factor Dp-2 (E2F dimerization partner 2)
chr3_-_27764197	2.299		EOMES	eomesodermin
chr1_-_221915426	2.294		DUSP10	dual specificity phosphatase 10
chr14_-_23755232	2.293		HOMEZ	homeobox and leucine zipper encoding
chr22_+_38054701	2.285	NM_020315	PDXP	pyridoxal (pyridoxine, vitamin B6) phosphatase
chr15_-_99551023	2.279	NM_001167902	PGPEP1L	pyroglutamyl-peptidase I-like
chr4_+_71494460	2.278	NM_031889	ENAM	enamelin
chr1_+_43148105	2.271		YBX1	Y box binding protein 1
chr19_+_41770285	2.265		HNRNPUL1	heterogeneous nuclear ribonucleoprotein U-like 1
chr3_+_42846075	2.265
chr1_+_52082755	2.248		OSBPL9	oxysterol binding protein-like 9
chr2_-_128784736	2.238		SAP130	Sin3A-associated protein, 130kDa
chr4_-_185726865	2.236		ACSL1	acyl-CoA synthetase long-chain family member 1
chr17_+_72744794	2.229		SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr11_-_64684606	2.226	NM_015104	ATG2A	ATG2 autophagy related 2 homolog A (S. cerevisiae)
chr1_-_11322543	2.224		MTOR	mechanistic target of rapamycin (serine/threonine kinase)
chr1_+_28585959	2.220	NM_031459	SESN2	sestrin 2
chr3_-_160283166	2.219		KPNA4	karyopherin alpha 4 (importin alpha 3)
chr17_+_4613780	2.218	NM_004313 NM_199004	ARRB2	arrestin, beta 2
chr20_-_60982334	2.216	NM_031215	CABLES2	Cdk5 and Abl enzyme substrate 2
chr16_-_11891100	2.215	NM_014153	ZC3H7A	zinc finger CCCH-type containing 7A
chr16_+_50776012	2.208	NM_001042412	CYLD	cylindromatosis (turban tumor syndrome)
chr5_+_70883179	2.207		MCCC2	methylcrotonoyl-CoA carboxylase 2 (beta)
chr11_-_67275549	2.203		CDK2AP2	cyclin-dependent kinase 2 associated protein 2
chr1_-_11322594	2.202		MTOR	mechanistic target of rapamycin (serine/threonine kinase)
chr5_+_70883137	2.201		MCCC2	methylcrotonoyl-CoA carboxylase 2 (beta)
chr9_-_35814997	2.192		HINT2	histidine triad nucleotide binding protein 2
chr10_-_101190201	2.185	NM_002079	GOT1	glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)
chr11_-_47198420	2.177		ARFGAP2	ADP-ribosylation factor GTPase activating protein 2
chr10_-_120101805	2.174	NM_001134672 NM_022063	FAM204A	family with sequence similarity 204, member A
chr12_-_26985922	2.173	NM_002223	ITPR2	inositol 1,4,5-trisphosphate receptor, type 2
chr19_+_41770336	2.164		HNRNPUL1	heterogeneous nuclear ribonucleoprotein U-like 1
chr1_-_36023002	2.159		KIAA0319L	KIAA0319-like
chr8_-_70745403	2.155	NM_001146009	SLCO5A1	solute carrier organic anion transporter family, member 5A1
chrX_+_46696474	2.154		RP2	retinitis pigmentosa 2 (X-linked recessive)
chr1_-_36022938	2.154		KIAA0319L	KIAA0319-like
chr1_+_52195508	2.132		OSBPL9	oxysterol binding protein-like 9
chr1_+_150459913	2.130	NM_025150	TARS2	threonyl-tRNA synthetase 2, mitochondrial (putative)
chr1_+_44173217	2.118	NM_006279 NM_174963 NM_174964 NM_174965 NM_174966 NM_174967 NM_174968 NM_174969 NM_174970 NM_174971	ST3GAL3	ST3 beta-galactoside alpha-2,3-sialyltransferase 3
chr17_+_72744775	2.118		SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr5_+_70883132	2.113		MCCC2	methylcrotonoyl-CoA carboxylase 2 (beta)
chr17_-_47841517	2.108	NM_030802	FAM117A	family with sequence similarity 117, member A
chr7_-_100183753	2.104	NM_002319	LRCH4	leucine-rich repeats and calponin homology (CH) domain containing 4
chr19_-_54663434	2.103	NM_024316	LENG1	leukocyte receptor cluster (LRC) member 1
chrX_-_48957985	2.095	NM_007075	WDR45	WD repeat domain 45
chr22_-_39152008	2.082	NM_001199579 NM_015374	SUN2	Sad1 and UNC84 domain containing 2
chr17_-_17942326	2.073	NM_145691	ATPAF2	ATP synthase mitochondrial F1 complex assembly factor 2

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
1.43	1.15e-08	GO:0008152	metabolic process
1.45	1.13e-07	GO:0044238	primary metabolic process
1.45	2.57e-07	GO:0044237	cellular metabolic process
1.50	5.98e-05	GO:0044260	cellular macromolecule metabolic process
1.72	9.69e-05	GO:0009058	biosynthetic process
1.61	1.38e-04	GO:0034641	cellular nitrogen compound metabolic process
1.82	6.14e-04	GO:0044281	small molecule metabolic process
1.56	7.81e-04	GO:0006807	nitrogen compound metabolic process
1.68	7.99e-04	GO:0044249	cellular biosynthetic process
1.62	9.05e-04	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.41	9.88e-04	GO:0043170	macromolecule metabolic process
1.18	1.46e-03	GO:0009987	cellular process
1.63	2.23e-03	GO:0044267	cellular protein metabolic process
8.76	3.58e-03	GO:0016126	sterol biosynthetic process
9.10	1.17e-02	GO:0006695	cholesterol biosynthetic process
4.26	1.56e-02	GO:0006323	DNA packaging
2.31	1.85e-02	GO:0051276	chromosome organization
2.52	2.12e-02	GO:0006325	chromatin organization
1.65	2.48e-02	GO:0043412	macromolecule modification
1.67	3.02e-02	GO:0006464	protein modification process
1.49	3.39e-02	GO:0019538	protein metabolic process

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
1.44	1.42e-16	GO:0043227	membrane-bounded organelle
1.43	2.99e-16	GO:0043231	intracellular membrane-bounded organelle
1.38	7.55e-16	GO:0043226	organelle
1.37	1.41e-15	GO:0043229	intracellular organelle
1.28	5.75e-14	GO:0044424	intracellular part
1.26	1.70e-12	GO:0005622	intracellular
1.59	3.62e-12	GO:0005634	nucleus
1.52	8.64e-10	GO:0044422	organelle part
1.53	8.71e-10	GO:0044446	intracellular organelle part
1.33	1.16e-07	GO:0005737	cytoplasm
1.42	5.78e-07	GO:0044444	cytoplasmic part
1.80	3.22e-06	GO:0070013	intracellular organelle lumen
1.79	4.02e-06	GO:0043233	organelle lumen
1.78	4.26e-06	GO:0031974	membrane-enclosed lumen
1.73	8.60e-05	GO:0044428	nuclear part
2.31	5.18e-04	GO:0031967	organelle envelope
2.27	7.83e-04	GO:0031975	envelope
1.88	8.68e-04	GO:0005739	mitochondrion
2.46	9.59e-04	GO:0005694	chromosome
3.38	9.68e-04	GO:0005792	microsome
3.27	1.58e-03	GO:0042598	vesicular fraction
2.23	2.89e-03	GO:0044429	mitochondrial part
1.67	3.89e-03	GO:0031981	nuclear lumen
1.60	6.64e-03	GO:0005829	cytosol
2.37	1.56e-02	GO:0044427	chromosomal part
1.73	2.15e-02	GO:0005654	nucleoplasm
1.54	2.41e-02	GO:0031090	organelle membrane
2.83	2.92e-02	GO:0005759	mitochondrial matrix
2.90	3.54e-02	GO:0000785	chromatin
2.83	4.53e-02	GO:0005635	nuclear envelope

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
1.17	7.25e-05	GO:0005488	binding
1.27	2.24e-03	GO:0005515	protein binding
5.27	5.87e-03	GO:0031625	ubiquitin protein ligase binding
2.12	6.05e-03	GO:0019899	enzyme binding
1.32	8.84e-03	GO:0003824	catalytic activity
1.40	4.36e-02	GO:0003676	nucleic acid binding